Short-term Outcomes of Laparoscopic vs.Open Hepatectomy for Primary Hepatocellular Carcinoma:A Prospective Comparative Study

作     者：Li ZENG Min TIAN Si-si CHEN Yu-ting KE Li GENG Sheng-li YANG Lin YE 

作者机构：Department of Hepatobiliary SurgeryUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Cancer CenterUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Gastrointestinal SurgeryUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China 

出 版 物：《Current Medical Science》 (当代医学科学（英文）)

年 卷 期：2019年第39卷第5期

页      面：778-783页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100214[医学-肿瘤学] 10[医学] 

基　　金：This project was supported by grants from Hubei Province Health and Family Planning Scientific Research Project,China(No.WJ2017Q023) Natural Science Foundation of Hubei Province,China(No.2016CFB356). 

主　　题：laparoscope open hepatectomy primary hepatocellular carcinoma short-term outcomes prospective comparative study 

摘      要：Laparoscopic hepatectomy(LH)is a newly developed technique associated with advantages as open surgery,but the study on outcome of liver function recovery was scarce.This preliminary report was aimed to comparatively assess the short?term outcomes between LH and open hepatectomy(OH)for primary hepatocellular carcinoma(PHC).This study retrospectively analyzed the demographic data and short-term outcomes of 81 patients who underwent LH or OH for the primary treatment of PHC between Oct.2017 and May 2018 at Union Hospital,Tongji Medical College,Huazhong University of Science and Technology(China).A total of 81 PHC patients who received major liver resection were enrolled.There were 38(47%)patients in the LH group and 43(53%)patients in the OH group.The operative time was significantly longer(373.53±173.38 vs.225.43±55.08,P0.01),and hospital stay(17.34±5.93 vs.21.70±6.89,P=0.003),exhaust time(2.32±0.62 vs.3.07±0.59,P0.01)and defecation time(2.92±0.78 vs.3.63±0.58,P0.01)were significantly shorter in LH group than in OH group.The recovery of liver function was significantly faster in LH group,including higher serum albumin(P=0.002),higher ratio of albumin/globulin(P=0.029)and lower direct bilirubin(P=0.001)than in OH group.It is suggested that LH can serve as a fast recovery and cheap surgical procedure in the treatment of PHC,which is safe and feasible.