Effects of Neurexan on Stress-Induced Changes of Spectral EEG Power: A Double-Blind, Randomized, Placebo-Controlled, Crossover Exploratory Trial in Human Volunteers

作     者：Wilfried Dimpfel 

作者机构：Justus-Liebig-University Giessen c/o NeuroCode AG Wetzlar Germany 

出 版 物：《World Journal of Neuroscience》 (神经科学国际期刊（英文）)

年 卷 期：2019年第9卷第3期

页      面：100-112页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Stress Anxiety qEEG Brain Map Brainwave Frequency Homeopathy Neurexan Nx4 

摘      要：Neurexan is a multicomponent natural medicinal product?used?for?stress-related?symptoms such as nervous restlessness and insomnia. The present study?investigated?the?efficacy?of Neurexan on stress-induced changes of brainwave frequencies?using quantitative analysis of spectral EEG power. Thirty healthy male and female volunteers were tested in a randomized, placebo controlled cross-over trial under conditions of relaxation and experimental stress-in-?duction. Recording of the EEG was performed over four hours after drug administration. Data was?analyzed using the proprietary fast dynamic EEG technology Neurocode-Tracking. Quantitative EEG revealed a task dependent increase of beta2 power as a surrogate parameter of stress induced anxiety. The elevated frontotemporal beta2 power was ameliorated by intake of Neurexan during the second and third hour after administration. This indicates that Neurexan is effectively helping subjects to better cope with task-related stress situations.