Association between the Consumption of Carbonated Beverages and Out-of-Hospital Cardiac Arrests of Cardiac Origin in Japan

作     者：Masaki Tokunaga Yasunori Suematsu Shin-ichiro Miura Takashi Kuwano Atsushi Iwata Hiroaki Nishikawa Bo Zhang Naohiro Yonemoto Hiroshi Nonogi Ken Nagao Takeshi Kimura Keijiro Saku 

作者机构：Department of Cardiology Fukuoka University School of Medicine Fukuoka Japan The AIG Collaborative Research Institute of Cardiovascular Medicine Fukuoka University Fukuoka Japan Department of Biochemistry Fukuoka University School of Medicine Fukuoka Japan Department of Epidemiology and Biostatistics National Center of Neurology and Psychiatry Tokyo Japan Hospital Deputy Shizuoka General Hospital Shizuoka Japan Department of Cardiology Resuscitation and Emergency Cardiovascular Care Surugadai Nihon University Hospital Nihon University School of Medicine Tokyo Japan Department of Cardiovascular Medicine Graduate School of Medicine Kyoto University Kyoto Japan 

出 版 物：《World Journal of Cardiovascular Diseases》 (心血管病（英文）)

年 卷 期：2015年第5卷第12期

页      面：361-372页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Out-of-Hospital Cardiac Arrest Utstein Registry Carbonated Beverage Ecological Study 

摘      要：Background: The consumption of carbonated beverages has been shown to increase the risk of developing metabolic syndrome. The associations between the consumption of carbonated beverages and left arterial dimension or left ventricular mass are believed to be likely related to the greater body weight of carbonated beverage drinkers relative to non-drinkers. Nonetheless, little is known about the association between the consumption of carbonated beverages and out-of-hospital cardiac arrests (OHCAs) in Japan. Methods: We compared the age-adjusted incidence of OHCAs to the expenditures on various beverages per person between 2005 and 2011 in the 47 prefectures of Japan. Patients who suffered from OHCAs of cardiac and non-cardiac origin were enrolled in All-Japan Utstein Registry of the Fire and Disaster Management Agency. The expenditures on various beverages per person in the 47 prefectures in Japan were obtained from data published by the Ministry of Health, Labour and Welfare of Japan. Results: There were 797,422 cases of OHCA in the All-Japan Utstein registry between 2005 and 2011, including 11,831 cases who did not receive resuscitation. Among these 785,591 cases of OHCA, 435,064 (55.4%) were classified as cardiac origin and 350,527 (44.6%) were non-cardiac origin. Non-cardiac origin included cerebrovascular disease, respiratory disease, malignant tumor, and exogenous disease (4.8%, 6.1%, 3.5%, and 18.9%, respectively). The expenditures on carbonated beverages were significantly associated with OHCAs of cardiac origin (r = 0.30, p = 0.04), but not non-cardiac origin (r = -0.03, p = 0.8). Expenditures on other beverages, including green tea, tea, coffee, cocoa, fruit or vegetable juice, fermented milk beverage, milk beverage, and mineral water, were not significantly associated with OHCAs of cardiac origin. Conclusion: Carbonated beverage consumption was significantly and positively associated with OHCAs of cardiac origin in Japan, indicating that beverage habits mi