Moderate/severe traumatic brain injury as a trigger of chronic neurodegeneration in humans

作     者：Sergio Bagnato Cristina Boccagni Sergio Bagnato;Cristina Boccagni

作者机构：Unit of Neurophysiology and Unit for Severe Acquired Brain Injuries Rehabilitation Department Giuseppe Giglio Foundation 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2020年第15卷第7期

页      面：1247-1248页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：acute damage injury 

摘      要：Traumatic brain injury(TBI)is the paradigmatic example of acute brain injury,defined as sudden and unexpected structural and/or functional damage to the *** western countries,TBI is a main cause of prolonged disability,and it is even more impactful because it very often affects young *** to past belief,the cerebral damage caused by TBI is not limited to the short temporal phase following the mechanical ***,moderate/severe TBI can trigger several mechanisms of neuronal damage that operate for months or years after the acute injury,potentially leading to neuronal loss and brain atrophy.