Undifferentiated Uterine Sarcoma: A Rare Cause of Pelvic Pain in Young Woman

作     者：Fenohery Nalisoa Rakotondrainibe Zo Irène Raivoherivony Nantenaina Soa Randrianjafisamindrakotroka 

作者机构：Pathological Anatomy Unit of Anosiala University Hospital Antananarivo Madagascar Pathological Anatomy Unit of Joseph Ravoahangy Andrianavalona University Hospital Antananarivo Madagascar 

出 版 物：《Open Journal of Pathology》 (病理学期刊（英文）)

年 卷 期：2019年第9卷第4期

页      面：71-75页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Sarcoma Endometrial Stroma Uterine Sarcoma 

摘      要：We report a case of undifferentiated uterine sarcoma occurring in a 20-year-old woman presenting as a pelvic pain with a mass discovered at the physical examination. The tumor ruptured into the abdominal cavity. A total hysterectomy was performed. On the pathological examination, the uterine corpus presents a proliferation of markedly atypical spindle cells admixed with round cells and pleomorphic cells. The tumor deeply infiltrated the myometrium. The tumor was very necrotizing. There were more than 50 mitoses per 10 fields at high magnification. The isthmus was invaded by the tumor. The diagnosis of undifferentiated uterine sarcoma was confirmed by immunohistochemistry. The tumor shows negativity for the following markers: CKAE1/AE3, h-caldesmon, α-SMA, progesterone receptors, desmin, CD 10, alpha foeto-protein, CD 3 and CD 20.