Role of the NLRP3 inflammasome in neurodegenerative diseases and therapeutic implications

作     者：Yanhui Duan Nathan Kelley Yuan He Yanhui Duan;Nathan Kelley;Yuan He

作者机构：Department of Biochemistry Microbiology and Immunology Wayne State University School of Medicine 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2020年第15卷第7期

页      面：1249-1250页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：the NLRP3 inflammasome in the He laboratory was funded by NIH grant K22AI120988 Wayne State University Startup 

主　　题：NLRP3 diseases degenerative 

摘      要：Neurodegenerative diseases are a group of neuronal disorders caused by progressive neuronal cell death in different regions of the human *** s disease(AD)and Parkinson s disease(PD)are the most common types of neurodegenerative diseases that affect millions of people *** is no cure available for either *** of the pathological hallmarks of neurodegenerative diseases is the abnormal protein aggregation in the central nervous system.