Overview of the special issue on HBV immunity
Overview of the special issue on HBV immunity作者机构：Emerging infectious Diseases Duke-NUS Medi-cal School Singapore Singapore SingaporeInstitute for Clinical Sciences A'STAR SingaporeSingapore and Research Center for BiologicalTherapy The Institute of Translational HepatologyBeijing China
出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)
年 卷 期：2015年第12卷第3期
页 面：253-254页
核心收录：
学科分类：0710[理学-生物学] 090502[农学-动物营养与饲料科学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 08[工学] 0905[农学-畜牧学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种]
摘 要：Hepatitis B virus （HBV） has a unique rela- tionship with humans. It is not only very suc- cessful in spreading amongst our species （a third of the human population has been in contact with the virus and approximately 200-300 million people are actively infected）, but it has adapted to and co-evolved with us. This long-term relationship is demonstrated by the recent detection of hepadnavirus gen- omes in Mesozoic birds2 and by the estima- tion that HBV was already present in early humans at least 40, 000 years ago.3
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