磁共振成像技术研究先天性纤维化综合征和协同肌分离患者的先天动眼神经发育不全及外展神经缺失

作     者：Kim J.H. Hwang J.-M. 宋虎平 

作者机构：Department of Ophthalmology Seoul Natl. Univ. Coll. of Medicine SeoulNatl. Univ. BundangHospital 300Gumi-dongBun dang-gu Seongnam Gyeonggi-do 463-707 South KoreaDr. 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2005年第1卷第11期

页      面：58-59页

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：磁共振成像技术 协同肌 发育不全 眼外肌 核磁共振成像 神经病理 眼科检查 薄层扫描 发育不良 理性报 

摘      要：Objective: There is only one neuropathologic report of congenital fibrosis of the extraocular muscles (CFEOM), and none of synergistic divergence. The aim of this report was to study the oculomotor nerve and the abducens nerve in 2 such p atients with magnetic resonance imaging. Design: Observational case reports. Met hods: Ophthalmologic examination and thin-sectioned magnetic resonance imaging across the brainstem level were performed in 2 patients with CFEOM and synergist ic divergence. To confirm the accuracy of the procedure, we compared the results obtained with those of a control group of 40 individuals using the same techniq ue. Main Outcome Measures: The oculomotor nerve and the abducens nerve on magnet ic resonance imaging. Results: Magnetic resonance imaging disclosed bilateral hy poplasia of the oculomotor nerve in both patients, and absence of the abducens n erve on the affected side of synergistic divergence. The oculomotor and abducens nerves were observed in 80 of 80 eyes (100%) screened as controls. C onclusions: In both patients with CFEOM and synergistic divergence, the oculomot or nerve was hypoplastic bilaterally, and the abducens nerve was absent on the s ide exhibiting synergistic divergence.