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Polarizing the immune system towards neuroprotection in brain ischemia

Polarizing the immune system towards neuroprotection in brain ischemia

作     者:Diana Amantea 

作者机构:Department of Pharmacy Health and Nutritional Sciences University of Calabria 

出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))

年 卷 期:2016年第11卷第1期

页      面:81-82页

核心收录:

学科分类:1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主  题:profiling innate modulated Brooks participate phenotype macrophages immediately microglia dramatically 

摘      要:The development of ischemic brain damage is dramatically affected by the immune system,whose activation occurs immediately after the insult and may last for several days,involving a complex interplay between soluble and cellular mediators(Amantea et al.,2015).Accordingly,recent expression profiling studies have revealed that the majority of the genes modulated in the blood of stroke patients participate in the regulation of innate immune responses(Brooks et al.,2014).

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