Fatal case of human rabies infection: A case report

作     者：Seyed Abbas Hosseinalipour Faranak Firoozfar Abedin Saghafipour Nazanin Ziasheikholeslami 

作者机构：Qom Provincial Health CenterQom University of Medical SciencesQomIran Vector-borne Diseases Research CenterNorth Khorasan University of Medical SciencesBojnurdIran Department of Public HealthFaculty of HealthQom University of Medical SciencesQomIran Department of Infectious DiseasesFaculty of MedicineQom University of Medical SciencesQomIran 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2019年第12卷第11期

页      面：528-530页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：supported from the Centre for Disease Control&Prevention of Qom Qom University of Medical Sciences 

主　　题：Animal bite Preventive measures Rabies Iran 

摘      要：Rationale:Rabies,as an acute viral disease of the mammal’s central nervous system(CNS),with a high mortality rate,is transmitted to humans through the bite of a rabid animals,especially canine and *** concerns:An Afghan man,aged 50 years was bitten by a fox in a farm around the Qom-Tehran road,Central Iran in *** patient visited the doctor after the bite,however the period between incidence and hospital visit was not established and no indication was given whether the bite site injury was thoroughly *** patient was neither referred to the health center for vaccination(post-exposure prophylaxis)nor an effective therapeutic measures was ***-five days post-exposure,the patient presented with symptoms such as headache,fever,tingling and burning sensation and was referred to the Centers for Disease Control and Prevention(CDC)unit of Qom Provincial Health ***:Rabies ***:Forty-five days after the animal bite,in CDC of Qom Health Center,he received rabies post-exposure prophylaxis treatment and was referred to an infectious diseases *** on the history of animal bites,the patient was classified as probable case of *** clinical symptoms of rabies appeared in patient after ***:Ultimately the patient died in hospital 4 days after hospitalization(50 days after the occurrence of animal bite).After referring the patient to the CDC,the patient’s saliva(0.5-1 mL)was sampled three times every 3-6 hours and tested by *** rabies was confirmed by Department of Virology in the Pasteur Institute of ***:Physicians and clinicians have responsibilities to be critical in observations and take prompt actions in case of animal bites,as rabies usually develops within 7 to 14 days,and delayed intervention after the onset of symptoms,vaccine and serum injections cannot lead to the survival of the patient.