Measurement and Influence Factors of the Flowability of Microcapsules with High-content β-Carotene
Measurement and Influence Factors of the Flowability of Microcapsules with High-content β-Carotene作者机构:Department of Chemical and Biochemical Engineering Zhejiang University Hangzhou 310027 China Xinchang Pharma. Factory Zhejiang Medical Co. Ltd. Xinchang 312500 China
出 版 物:《Chinese Journal of Chemical Engineering》 (中国化学工程学报(英文版))
年 卷 期:2007年第15卷第4期
页 面:579-585页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 100704[医学-药物分析学] 10[医学]
基 金:Supported by the National-Natural Science Foundation of China (No.20576118) and National High Technology Research and Development Program of China (863 Program No.2006AA02Z210)
主 题:β-carotene microcapsule powders flowability Hausner ratio repose angle
摘 要:The flowability of five kinds of microencapsulation powders,with differentβ-carotene contents and by two alternative particle-forming technologies ***-drying and starch-catching beadlet technology,was meas- *** actual flow properties of the five powders were compared based on bin-flow test,and three flow indexes (Hausner ratio,repose angle and flow index)were *** was found that the repose angle is the most suitable index to reflect the flowability of these powders for the particle properties would not be altered due to compaction or tapping during the measuring *** size and particle size distribution play most important roles in the flowability of these granular materials,which was also influenced by other factors like shape,surface texture,sur- face roughness,*** with wall material of gelatin and a layer of modified starch absorbed on the sur- face showed excellent flowabilities and good mechanical properties,and they are favorable for tabletting to supply β-carotene.