晶状体乳化联合可拆除缝线小梁切除术的安全性和有效性
The safety and efficacy of combined phacoemulsification and trabeculectomy with releasable sutures作者机构：600 N Wolfe Street Baltimore MD 21287 United States Dr.
出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)
年 卷 期：2006年第2卷第5期
页 面：17-18页
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
主 题：小梁切除术后 晶状体乳化 可拆除缝线 安全性 联合 人工晶状体植入 青光眼药物 矫正视力 抗代谢药物 回顾性分析
摘 要：Aim: To evaluate the combined phacoemulsification with acrylic intraocular lens implantation and trabeculectomy with releasable sutures, without the use of antimetabolites, performed by one surgeon. Methods: A retrospective analysis was performed on 251 eyes of 198 patients after a combined phaco/trabeculectomy procedure, followed up for an average of 16 months for vision, intraocular pressure (IOP), and number of glaucoma medications. Cox proportional hazard regression analysis provided measures of relative risk (RR) or hazards ratios and 95%confidence intervals (CIs) associated with the occurrence of several conditions or complications of surgery. Results: Mean preoperative variables were best corrected vision, 0.6 (SD 0.4) logMAR(20/80 Snellen); IOP, 18.7 (4.9)mmHg; and number of glaucoma medications, 1.7 (0.8). Mean postoperative results were best corrected vision, 0.2 (0.4) logMAR (20/32 Snellen); IOP, 15.1 (3.2) mm Hg; and number of glaucoma medications, 0.3 (0.6). Postoperatively, the mean decreases from baseline were 19.2%for IOP and 84.1%for number of glaucoma medications; 85%of eyes required fewer glaucoma medications and 78%of eyes were medication free, with IOP control. There were no significant operative or postoperative complications. Conclusion: Combined phacoemulsification and trabeculectomy with releasable sutures, in the absence of antimetabolites, is a safe, effective, and stable alternative for patients with cataracts and glaucoma.
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