Metachronous intracystic and intraductal papillary neoplasms of the biliary tree

作     者：Hirohide Sato Yasunori Sato Kenichi Harada Motoko Sasaki Katsuyasu Hirano Yasuni Nakanuma 

作者机构：Department of Human PathologyKanazawa University Graduate School of Medicine Department of Surgery Wajima Hospital 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2013年第19卷第36期

页      面：6125-6126页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Intraductal papillary neoplasm Intracystic papillary neoplasm Gastric type Metachronous occurrence Synchronous occurrence 

摘      要：A 77-year-old woman complained of epigastralgia,and a tumor(5 cm in diameter)of the gallbladder neck was detected by image analysis.Following cholecystectomy,the tumor was pathologically diagnosed as intraductal papillary neoplasm(IPN),gastric type,with associated invasive carcinoma.About 10 mo later,intraluminal multiple masses(3 foci,up to 1.8 cm)were noted in the extrahepatic bile duct,and the resected specimen showed that all tumors had similar gross and microscopic features as seen in gallbladder IPN without invasion,and they were synchronous multiple lesions.This case showed a papillary tumor of the gallbladder of gastric phenotype,and confirmed that the gallbladder is a target of IPN in addition to the bile ducts.