Histopathology of nonalcoholic fatty liver disease

作     者：Elizabeth M Brunt Dina G Tiniakos 

作者机构：Department of Pathology and ImmunologyWashington University School of MedicineSt.LouisMO 63110United States Laboratory of Histology and EmbryologyMedical SchoolNational and Kapodistrian University of AthensAthens 11527Greece 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2010年第16卷第42期

页      面：5286-5296页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：NCI NIH HHS [P50 CA095817] Funding Source: Medline 

主　　题：Fatty liver Steatosis Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis Fibrosis 

摘      要：Histological analysis of liver biopsies remains a standard against which other methods of assessment for the presence and amount of hepatic injury due to nonalcoholic fatty liver disease(NAFLD) are *** evaluation remains the sole method of distinguishing steatosis from advanced forms of NAFLD,*** steatohepatitis(NASH) and *** in the lesions of NAFLD are steatosis,lobular and portal inflammation,hepatocyte injury in the forms of ballooning and apoptosis,and ***,patterns of these lesions are as distinguishing as the lesions *** injury in adults and children due to NAFLD may have different histological *** this review,the rationale for liver biopsy,as well as the histopathological lesions,the microscopically observable patterns of injury,and the differential diagnoses of NAFLD and NASH are discussed.