The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer's disease: agonists or antagonists?

作     者：Rubina Marzagalli Alessandro Castorina 

作者机构：Department of Biomedical Sciences and Biotechnologies Section of Human Anatomy and Histology University of Catania 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2015年第10卷第2期

页      面：205-207页

核心收录：

学科分类：1002[医学-临床医学] 100203[医学-老年医学] 10[医学] 

主　　题：The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer’s disease agonists or antagonists 

摘      要：Alzheimer＇s disease （AD） is the most common neurodegenerative disorder, and its incidence is relatively high among elderly people, affecting about 1-2% of the population between 60-65 years old and rising dramatically （about 30%） in people aged 80 years or older （Selkoe, 2002）. Nowadays, considering the increasing mean lifespan of populations in developed countries, the disease is becoming more and more a health concern, and the search for an effective cure has turned into＂a real need＂.