Relationship between event-related potential P300 and first episode schizophrenia

作     者：CHEN Xing-shi LU Ying-zhi WANG Ji-jun WANG Hong-xing ZHANG Ming-dao LOU Fei-yin CHEN Chong 

作者机构：Department Of Electrophysiology Shanghai Mental Health Center Shanghai 200030China Depantment of Psychiatry Fifth People＇s Hospital Zibo 255120Shandong Province China Department of Electronic EphalographySource Imaging Shanghai Mental Health Center Shanghai 200030China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2007年第120卷第4期

页      面：339-341页

核心收录：

学科分类：1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学] 

基　　金：the Foundation of the Municipal Committee of Shanghai Science and Technology (No.054119534) the National Natural Science Foundation of China (No. 30470626) 

主　　题：schizophrenia event-relatedpotentials, P300 memory disorders 

摘      要：Although P300 abnormalities of event-related .potentials （ERPs） are consistently reported among schizophrenic patients as being the most compelling indices of their brain dysfunction, whether they are trait markers or state markers of schizophrenia remains in controversy. To shed a light on this point, we made a longitudinal study of P300 among first episode schizophrenic patients, from no medication until the patients had been medicated for 12 weeks.