Mechanisms of Ketone/Imine Hydrogenation Catalyzed by Transition-Metal Complexes

作     者：Yangqiu Liu Xin Yue Chenguang Luo Lin Zhang Ming Lei Yangqiu Liu;Xin Yue;Chenguang Luo;Lin Zhang;Ming Lei

作者机构：State Key Laboratory of Chemical Resource EngineeringInstitute of Computational ChemistryCollege of ChemistryBeijing University of Chemical TechnologyBeijing 100029China 

出 版 物：《Energy & Environmental Materials》 (能源与环境材料（英文）)

年 卷 期：2019年第2卷第4期

页      面：292-312页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by National Natural Science Foundation of China(Nos.21672018 and 2161101308) the Fundamental Research Funds for the Central Universities(XK1802-6) 

主　　题：density functional theory hydrogenation dehydrogenation reaction mechanism 

摘      要：Alcohols and amines are important in pharmaceutical, perfume, and agrochemical industries. Catalytic asymmetric synthesis is one of the major ways to produce chiral alcohols/amines from prochiral ketones/imines via hydrogenation. Meanwhile, the alcohol/amine dehydrogenation with high hydrogen energy density is paid more and more attention as promising hydrogen-storage media. In this review, we summarize classifications of mechanisms of ketone/imine hydrogenation and alcohol/amine dehydrogenation catalyzed by transition-metal (TM) complexes, the H2activation modes, and the nature of asymmetric ketone/imine hydrogenation (AKH/AIH). This will elaborate our understanding on the nature of the TM-catalyzed ketone/imine hydrogenation and alcohol/amine dehydrogenation reactions.