Chemical constituents and ACE inhibitory activity of desert plant Suaeda physophora Pall.

作     者：Ruizhi Men Ning Li Yachao Xing Yingzhan Tang Chengyu Tan Fantong Meng Juan Zhang Hui Ni Xiaoguang Jia 

作者机构：Key Laboratory of Structure-Based Drug Design&Discovery of Ministry of EducationSchool of Traditional Chinese MedicineShenyang Pharmaceutical UniversityShenyang 110016China Marine Environmental Engineering CollegeDalian Ocean UniversityDalian 116023China Xinjiang Institute of Chinese Materia Medica and EthnodrugUrumqi 830002China 

出 版 物：《Acta Pharmaceutica Sinica B》 (药学学报（英文版）)

年 卷 期：2013年第3卷第5期

页      面：328-332页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China(81001371) the Science and Technology Foundation of Dalian city(2011J21DW012) 

主　　题：Desert plant Suaeda physophora Pall. Chemical constituents ACE inhibitory activity 

摘      要：Suaeda physophora *** a kind of desert plant mostly growing in saline habitats in Xinjiang Uygur Autonomous *** order to have a better utilization of halophytes,a screening for ACE inhibitors from halophytes growing in Xinjiang was carried *** result showed that the 70%EtOH extract and n-BuOH extract of *** *** significant ACE inhibitory *** we focused on its biochemical constituents *** new quinazoline alkaloid,namely Suaedine(1),along with six known compounds(2–7)was isolated from the aerial parts of *** *** structure of the new quinazoline alkaloid was established by one-and two-dimensional nuclear magnetic resonance,optical rotation and mass spectrometry *** flavonoid compounds(2–4)and phenolic compound(5)exhibited significant ACE *** was the first time to focus on the chemical constituents and bioactivities of this plant.