Three-component one-pot synthesis of 1,2,3,4-tetrahydroquinoline derivatives in hexafluoroisopropanol
Three-component one-pot synthesis of 1,2,3,4-tetrahydroquinoline derivatives in hexafluoroisopropanol作者机构：Institute of Materia Medica Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100050 China
出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)
年 卷 期：2008年第19卷第8期
页 面：921-924页
核心收录：
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金：the National Natural Science Foundation of China(No.30672540) NSF of Beijing(No.7072048)for financial support
主 题：Aza-Diels-Alder reaction Tetrahydroquinoline Hexafluoroisopropanol (HFIP) Fluorinated solvent
摘 要：The one-pot aza-Diels-Alder reaction of substituted aromatic amines, ethyl glyoxylate and benzyl vinylcarbamate or N- benzyloxycarbonyl 2-pyrroline was conducted in hexafluoroisopropanol, providing the desired 1,2,3,4-tetrahydroquinline derivatives in moderate yields.
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