Effects of Pemetrexed and Docetaxel Combined with Cisplatin in the Treatment of Non-small Cell Lung Cancer
作者机构：Tianjin Chest HospitalTianjin300052China Tianjin Medical University General HospitalTianjin300052China
出 版 物：《Proceedings of Anticancer Research》 (抗癌研究)
年 卷 期：2018年第2卷第3期
页 面：19-22页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：pemetrexed docetaxel cisplatin non-small cell lung cancer
摘 要：The purpose of this study was to compare the clinical effects of pemetrexed and docetaxel combined with cisplatin in the treatment of patients with non-small cell lung cancer.A total of 58 patients with non-small cell lung cancer who were enrolled between January 2017 and January 2018 were enlisted into a randomized digital table.29 patients who have received treatment with combined pemetrexed and cisplatin were assigned to the pemetrexed group,whereas for the other 29 patients which were treated with docetaxel and cisplatin combined,were assigned to the docetaxel group to verify the calculated clinical treatment efficiency of the patients with non-small cell lung cancer,soluble vascular cell adhesion molecule 1(SVCAM-1),and activated leukocyte cell adhesion molecule-1(alCAM-1)concentrations and to evaluate the quality of life scores of the patients after half a year as well as the incidences of adverse reactions following the treatments *** differences in SVCAM-1 and alCAM-1 concentrations and incidence of adverse reactions in patients with non-small cell lung cancer in the docetaxel group as compared with patients in the pemetrexed group after the treatments were statistically significant(P0.05,demonstrated no analytical *** pemetrexed combined with cisplatin and docetaxel in combination with cisplatin as forms of treatments demonstrated significant effects in patients with non-small cell lung ***,based on our study,it was found that the combined treatment involvi
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