Synthesis,structural characterization and antibacterial activity of diorganotin(Ⅳ) complexes with ONO tridentate Schiff bases containing pyridine ring

作     者：Tahereh Sedaghat Razieh Habibi Hossein Motamedi Hamid Reza Khavasi 

作者机构：Department of ChemistryCollege of SciencesShahid Chamran University Department of BiologyCollege of SciencesShahid Chamran University Department of ChemistryShahid Beheshti UniversityG. C.Evin 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2012年第23卷第12期

页      面：1355-1358页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Support of this work by Shahid Chamran University Ahvaz Iran is gratefully acknowledged 

主　　题：Schiff base Antibacterial activity Organotin(IV) Crystal structure 119Sn NMR 

摘      要：Five organotin（IV） complexes, were obtained by reaction of SnR2C12 （R = Ph, Me, Bu） with ONO donor Schiff bases. The synthesized complexes have been investigated by elemental analysis and IR, 1H NMR, and ll9Sn NMR spectroscopy. These data show that the Schiff base acts as a tridentate dianionic ligand and coordinates via the imine nitrogen and two oxygen atoms. The X- ray crystallography of complex 4 shows a dimeric structure for this molecule. The in vitro antibacterial activities of the Schiff bases and their complexes have been evaluated against Gram-positive （Bacillus subtilis and Staphylococcus aureus） and Gram-negative （Escherichia coli and Pseudomonas aeruginosa） bacteria and compared with the standard antibacterial drugs.