Fine tuning of the default depth and rate of ablation of the epithelium in customized trans-epithelial one-step superficial refractive excimer laser ablation
作者机构：South Australian Institute of OphthalmologyUniversity of AdelaideAdelaideAustralia Brisbane Laser Sight ClinicBrisbaneAustralia Ashford Advanced Eye CareAdelaideAustralia iVis TechnologiesTarantoItaly
出 版 物：《Eye and Vision》 (眼视光学杂志（英文）)
年 卷 期：2019年第6卷第1期
页 面：331-337页
核心收录：
学科分类：080901[工学-物理电子学] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 080401[工学-精密仪器及机械] 0804[工学-仪器科学与技术] 0803[工学-光学工程]
基 金：Ethics submission financed by iVis Technologies
主 题：Transepithelial photorefractive keratectomy Epithelial ablation Epithelial thickness refinement Stromal ablation rate refinement
摘 要：Purpose:To fine tune the default depth and rate of ablation of the epithelium in cTen^(TM) customized trans-epithelial one-step superficial refractive surgery by the comparison between the attempted post-operative ideal corneal shape and the achieved corneal ***:88 consecutive eyes in 64 patients undergoing trans-epithelial superficial excimer ablation using the iVis laser Suite for either myopic/astigmatic or hyperopic/astigmatic refractive *** patient had at least 3 months of post-operative *** examination of all eyes was carried out pre-operatively and at least 3 months post-operatively using the Precisio^(TM) surgical *** comparison of these two measurements yielded values for depth,volumes and rates of ablated corneal *** determining the different ablation rates of stroma and epithelium,a refinement of the depth of epithelium to be removed and a refinement of the stromal ablation were *** mathematical model was applied on each one of the 88 clinical cases and the parameters for the fine tuning of the default depth and rate of ablation of the epithelium were determined using the least squares ***:The calculated pure stromal ablation rate was less than the average epithelium/stroma ablation rate used in planning the treatments by a factor of *** epithelial thickness predefined ablation assumption used to plan removal of the epithelium was adjusted considering the measured ablation and a radial adjustment function established for the fine tuning of the laser radial efficiency and allowing for the normal thickening of the epithelium in the peripheral *** a clinical point of view,this methodology produces an improvement of the efficacy and a reduction of the variance of the clinical ***:Comparison of accurately measured pre and postoperative topographies yields accurately established ablation rates of stroma and epithelium in trans-epithelial one step superficial a
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