Androgen receptor mutants detected in recurrent prostate cancer exhibit diverse functional characteristics

作     者：ChenG WangX ZhangS LuY SunY ZhangJ LiZ LuJ 

作者机构：DepartmentofPathophysiologySecondMilitaryMedicalUniversityShanghai200433China 

出 版 物：《第二军医大学学报》 (Academic Journal of Second Military Medical University)

年 卷 期：2006年第27卷第2期

页      面：119-119页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：雄激素受体 前列腺癌 临床表现 治疗 

摘      要：OBJECTIVE:Alterations in the function of androgen receptor (AR) and its signaling pathway may be responsible for the progression of prostate cancer. The goal of the present study was to investigate the potential roles of AR structural and functional alterations in the progression of prostate cancer, and the relationship between the structure and function of the AR.