Age-specific differences in non-cardiac comorbidities among elderly patients hospitalized with heart failure: a special focus on young-old, old-old, and oldest-old

作     者：Meng-Xi Yang Hui An Xue-Qiang Fan Li-Yuan Tao Qiang Tu Li Qin Li-Fang Zhang Dong-Ping Feng Yu Wang Li Sun Si Gao Wen-Zhuo Guan Jin-Gang Zheng Jing-Yi Ren Yang Meng-Xi;An Hui;Fan Xue-Qiang;Tao Li-Yuan;Tu Qiang;Qin Li;Zhang Li-Fang;Feng Dong-Ping;Wang Yu;Sun Li;Gao Si;Guan Wen-Zhuo;Zheng Jin-Gang;Ren Jing-Yi

作者机构：Department of CardiologyChina-Japan Friendship HospitalBeijing 100029China Department of CardiologyHebei General HospitalShijiazhuangHebei 050051China Department of Cardiovascular SurgeryChina-Japan Friendship HospitalBeijing 100029China Research Center of Clinical EpidemiologyPeking University Third HospitalBeijing 100191China State Key Laboratory for Molecular and Developmental BiologyInstitute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of SciencesBeijing 100039China Department of Laboratory MedicinePeking University People's HospitalBeijing 100044China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2019年第132卷第24期

页      面：2905-2913页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：This work was supported by the National Natural Science Foundation of China(81770359 and 81270276) Central Health Research Project of China(W2017BJ30) State Key Laboratory of Molecular Developmental Biology of China(2017-MDB-KF-13)to Jingyi Ren China-Japan Friendship Hospital Scientific Research Funds(2017-1-QN-10)to Mengxi Yang 

主　　题：Heart failure Elderly Non-cardiac comorbidity Polypharmacy 

摘      要：Background:Despite the growing epidemic of heart failure(HF),there is limited data available to systematically compare noncardiac comorbidities in the young-old,old-old,and oldest-old patients hospitalized for *** precise differences will add valuable information for better management of HF in elderly ***:A total of 1053 patients aged 65 years or older hospitalized with HF were included in this *** were compared among three age groups:(1)young-old:65 to 74 years,(2)old-old:75 to 84 years,and(3)oldest-old:≥85 *** details of presentation,comorbidities,and prescribed medications were ***:The mean age was 76.7 years and 12.7%were 85 years or *** elderly patients with HF(97.5%)had at least one of the non-cardiac *** patterns of common non-cardiac comorbidities were different between the young-old and oldestold *** three most common non-cardiac comorbidities were anemia(53.6%),hyperlipidemia(45.9%),and diabetes(42.4%)in the young-old group,while anemia(73.1%),infection(58.2%),and chronic kidney disease(44.0%)in the oldest-old *** was observed in 93.0%elderly patients with ***,29.2%patients were diagnosed with infection,and 67.0%patients were prescribed ***,60.4%patients were diagnosed with anemia with only 8.9%of them receiving iron ***:Non-cardiac comorbidities are nearly universal in three groups but obviously differ by age,and inappropriate medications are very common in elderly patients with *** treatment strategies should be focused on providing optimal medications for age-specific non-cardiac conditions.