Anxiety and depression propensities in patients with acute toxic liver injury

作     者：Jeong Ill Suh Jeong Kyu Sakong Kwan Lee Yong Kook Lee Jeong Bae Park Dong Joon Kim Yeon Seok SeoDepartment of Internal Medicine Korea University Anam Hospital Korea University College of Medicine Seoul 136-705 South Korea Jae Dong Lee Soon Young Ko Byung Seok Lee Seok Hyun Kim Byung Seok Kim Young Seok Kim Heon Ju Lee In Hee Kim Joo Hyun Sohn Tae Yeob Kim Byung Min Ahn 

作者机构：Department of Internal MedicineDongguk University Gyeongju HospitalDongguk University College of MedicineGyeongju 780-350South Korea Department of PsychiatryDongguk University Gyeongju HospitalDongguk University College of MedicineGyeongju 780-350South Korea Department of Preventive MedicineDongguk University College of MedicineGyeongju 780-350South Korea Department of Internal MedicineHallym University Medical CenterHallym University College of MedicineChuncheon 200-704South Korea Department of Internal MedicineKonkuk University Chungju HospitalKonkuk University College of MedicineChungju 380-704South Korea Department of Internal MedicineChungnam National University HospitalChungnam University College of MedicineDaejeon 301-721South Korea Department of Internal MedicineDaegu Catholic University Medical CenterDaegu Catholic University College of MedicineDaegu 705-718South Korea Department of Internal MedicineSoonchunhyang University Bucheon HospitalSoonchunhyang University College of MedicineBucheon 420-767South Korea Department of Internal MedicineYeungnam University Medical CenterYeungnam University College of MedicineDaegu 705-703South Korea Department of Internal MedicineChonbuk National University HospitalChonbuk National University College of MedicineJeonju 561-712South Korea Department of Internal MedicineHanyang University Guri HospitalHanyang University College of MedicineGuri 471-701South Korea Department of Internal MedicineHwain Metro HospitalChunan 331-959South Korea 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2013年第19卷第47期

页      面：9069-9076页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by Foundation of the Korean Association for the Study of the Liver Research Grant 

主　　题：Liver injury Herb Toxic Anxiety Depression 

摘      要：AIM:To investigate anxiety and depression propensities in patients with toxic liver ***:The subjects were divided into three groups:a healthy control group(Group 1,n=125),an acute non-toxic liver injury group(Group 2,n=124),and a group with acute toxic liver injury group caused by noncommercial herbal preparations(Group 3,n=126).These three groups were compared and evaluated through questionnaire surveys and using the Hospital Anxiety-Depression Scale(HADS),Beck Anxiety Inventory(BAI),Beck Depression Inventory(BDI),and the hypochondriasis ***:The HADS anxiety subscale was 4.9±2.7,5.0±3.0 and 5.6±3.4,in Groups 1,2,and 3,*** HADS depression subscale in Group 3 showed the most significant score(5.2±3.2,6.4±3.4 and 7.2±3.4in Groups 1,2,and 3,respectively)(P0.01 vs Group 1,P0.05 vs Group 2).The BAI and BDI in Group 3showed the most significant score(7.0±6.3 and 6.9±6.9,9.5±8.6 and 8.8±7.3,10.7±7.2 and 11.6±8.5in Groups 1,2,and 3,respectively)(BAI:P0.01 vs Group 1,P0.05 vs Group 2)(BDI:P0.01 vs Group1 and 2).Group 3 showed a significantly higher hypochondriasis score(8.2±6.0,11.6±7.5 and 13.1±6.5in Groups 1,2,and 3,respectively)(P0.01 vs Group 1,P0.05 vs Group 2).CONCLUSION:Psychological factors that present vulnerability to the temptation to use alternative medicines,such as herbs and plant preparations,are important for understanding toxic liver injury.