Multi-modality imaging in transthyretin amyloid cardiomyopathy
Multi-modality imaging in transthyretin amyloid cardiomyopathy作者机构：Department of CardiologyConnolly Hospital BlanchardstownAbbottstownDublin D15X40DIreland Department of CardiologySt George’s University Hospital NHS Foundation TrustLondon SW170QTUnited Kingdom
出 版 物：《World Journal of Cardiology》 (世界心脏病学杂志（英文版）（电子版）)
年 卷 期：2019年第11卷第11期
页 面：266-276页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Multimodality imaging Cardiac amyloidosis Transthyretin Echocardiography Cardiac magnetic resonance Nuclear imaging
摘 要：Transthyretin amyloid(TTR)cardiomyopathy is a disease of insidious onset,which is often accompanied by debilitating neurological and/or cardiac *** true prevalence is not fully known due to its elusive presentation,being often under-recognized and usually diagnosed only late in its natural history and in older *** of this,effective treatment options are usually precluded by multiple comorbidities and frailty associated with such ***,high clinical suspicion with earlier and better detection of this disease is *** this review,the novel applications of multimodality imaging in the diagnostic pathway of TTR cardiomyopathy are *** include the complimentary roles of transthoracic echocardiography,cardiac magnetic resonance,nuclear scintigraphy and positron emission tomography in quantifying cardiac dysfunction,diagnosis and risk *** advances in novel therapeutic options for TTR have further enhanced the importance of a timely and accurate diagnosis of this disease.
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