Genes for sexual body size dimorphism in hybrid tilapia(Oreochromis sp.x Oreochromis mossambicus)
作者机构：Molecular Population Genetics and Breeding GroupTemasek Life Sciences Laboratory1 Research LinkNational University of Singapore117604Singapore School of Biological SciencesNanyang Technological University60 Nanyang Drive637551Singapore Department of Biological SciencesNational University of Singapore14 Science Drive 4117543Singapore
出 版 物：《Aquaculture and Fisheries》 (渔业学报（英文）)
年 卷 期：2019年第4卷第6期
页 面：231-238页
学科分类：0710[理学-生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1002[医学-临床医学] 0908[农学-水产] 0707[理学-海洋科学] 100214[医学-肿瘤学] 0713[理学-生态学] 10[医学]
基 金：the National Research Foundation,Prime Minister's Office,Singapore,under its Competitive Research Program(CRP Award No.NRF-CRP7-2010-01) the internal fund of Temasek Life Sciences Laboratory,Singapore
主 题：Sexual dimorphism Body size RNA-Seq Tilapia Aquaculture Evolution
摘 要：Tilapias are important aquaculture ***-biased sexual size dimorphism is very common and males are preferred for aquaculture in ***,the mechanisms underlying sexual dimorphism remain to be *** hundred and thirty-six sex-biased genes,of which 23 were male-biased and 113 were femalebiased,were identified via reanalysis of a muscle transcriptome data using the latest reference genome *** genes were mapped to KEGG pathways that are related to somatic cell metabolism,growth and differentiations,such as MAPK,FoxO4 and metabolism pathways as well as developmental processes responsible for skeletal muscle *** related to cell growth and proliferations such as MAPK signaling pathways are upregulated in males while pathways regulating cell division such as FoxO4 are upregulated in ***-biased genes in tilapia skeletal muscle have higher evolution rates(dN/dS)compared to unbiased ***-biased and male-biased genes showed 17.4%and 13.5%higher dN/dS,respectively,compared to unbiased *** results suggest that some of the male and female sex-biased genes were under selection *** SNPs located in the promoter region of one sex-biased gene RASGRF1 on LG1 were associated with bodyweight differences in the hybrid *** sex-biased genes identified in this study may serve as candidate genes for future functional analysis on sexual size dimorphism and for developing DNA markers for selecting fast-growing saline tilapia in aquaculture.
维普期刊数据库