Epiphyseal distraction and hybrid reconstruction using polymethyl methacrylate construct combined with free non-vascularized fibular graft in pediatric patients with osteosarcoma around knee: A case report
Epiphyseal distraction and hybrid reconstruction using polymethyl methacrylate construct combined with free non-vascularized fibular graft in pediatric patients with osteosarcoma around knee: A case report作者机构：Department of OrthopaedicsXiangya Hospital Central South University
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2019年第7卷第21期
页 面：3632-3638页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by National Natural Science Foundation of China No.81301671
主 题：Epiphyseal distraction Custom-made polymethyl methacrylate construct Non-vascularized fibular graft Osteosarcoma Case report
摘 要：BACKGROUND In children with osteosarcoma around the knee joint without epiphysis involvement,joint-sparing surgery seems to be an ideal way to retain knee joint ***,there are two points of debate with regard to the technique:How to accurately achieve a safe surgical margin,and how to achieve intercalary reconstruction of the massive bone defect following resection of the *** SUMMARY We present the case of an 8-year-old girl with osteosarcoma of the distal femur without involvement of the *** distraction was applied to separate the epiphysis and metaphysis,and this provided a safe surgical *** massive bone defect was reconstructed with a custom-made antibioticloaded polymethyl methacrylate(PMMA)construct combined with a free nonvascularized fibular *** months after surgery,bone union between the autograft and host bone was confirmed in both the proximal and distal femur by computer tomography(CT)***,considerable callus formation was found around the PMMA *** 28 mo of follow-up,there was no sign of recurrence or *** patient could walk without any aid and carry out her daily life activities *** In cases of osteosarcoma without epiphysis involvement,epiphyseal distraction can be easily applied to obtain a safe *** reconstruction with an antibiotic-loaded PMMA construct combined with a free non-vascularized fibular graft has the advantages of being easy to manufacture,less time-consuming to place,and less likely to get infected,while also ensuring bone *** case provides an alternative technique for biological reconstruction after joint-sparing surgery in patients with osteosarcoma around the knee without epiphyseal involvement.
维普期刊数据库