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Low-velocity simultaneous bilateral femoral neck fracture following long-term antiepileptic therapy:A case report

Low-velocity simultaneous bilateral femoral neck fracture following long-term antiepileptic therapy:A case report

作     者:Mohammed Sadiq Vikrant Kulkarni Syed Azher Hussain Mohammed Ismail Mayur Nayak 

作者机构:Department of Orthopaedics ESIC Medical College 

出 版 物:《World Journal of Orthopedics》 (世界骨科杂志(英文版))

年 卷 期:2019年第10卷第10期

页      面:371-377页

学科分类:0403[教育学-体育学] 1002[医学-临床医学] 10[医学] 

主  题:Case report Bilateral femoral neck fracture Antiepileptic drug therapy Druginduced osteopenia Bisphosphonates Vitamin D 

摘      要:BACKGROUND Simultaneous bilateral femoral neck fractures are relatively rare *** are usually associated with underlying metabolic bone disorders or systemic ***-term use of narcotics and bisphosphonates can also result in similar fracture patterns;however,association of this fracture type with longterm use of antiepileptic drugs is not very *** one such case has been reported in the *** article describes the *** REPORT We report a case of simultaneous displaced bilateral femoral neck fractures in a 50-year-old epileptic patient,who had taken phenytoin for the past 3 *** fractures were a result of low-velocity injury following a fall from the *** fractures were managed with a bilateral hemi-replacement *** bisphosphonates were given to improve the bone quality in the post-operative *** patient had a good post-operative outcome,that was sustained throughout the entire follow-up period of 1 *** Antiepileptic drugs should be supplemented with bisphosphonates and vitamin D to improve bone quality and prevent fractures in epileptic patients.

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