Electroacupuncture at Baihui (DU20) acupoint upregulates mRNA expression of NeuroD molecules in the brains of newborn rats suffering in utero fetal distress

作     者：Lu Chen Yan Liu Qiao-mei Lin Lan Xue Wei Wang Jian-wen Xu 

作者机构：Neurobiology Research CenterDepartment of Human AnatomyHistology and EmbryologySchool of Basic Medical SciencesFujian Medical University 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2016年第11卷第4期

页      面：604-609页

核心收录：

学科分类：1005[医学-中医学] 100512[医学-针灸推拿学] 10[医学] 

基　　金：supported by the Natural Science Foundation of Fujian Province of China,No.2015J01133 the Professor Academic Development Foundation of Fujian Medical University of China,No.JS11003 

主　　题：nerve regeneration brain injury in utero fetal distress hypoxic ischemic brain injury electroacupuncture real time fluorescent quantitative PCR Neuro D nerve repair Baihui(DU20) acupoint non acupoint neural regeneration 

摘      要：Neuro D plays a key regulatory effect on differentiation of neural stem cells into mature neurons in the ***,we assumed that electroacupuncture at Baihui（DU20） acupoint in newborn rats exposed to in utero fetal distress would influence expression of Neuro *** at Baihui was performed for 20 minutes on 3-day-old（Day 3） newborn Sprague-Dawley rats exposed to in utero fetal distress;electroacupuncture parameters consisted of sparse and dense waves at a frequency of 2–10 ***-time fluorescent quantitative PCR results demonstrated that m RNA expression of Neuro D,a molecule that indicates Neuro D,increased with prolonged time in brains of newborn rats,and peaked on Day *** level of m RNA expression was similar between Day 16 and Day *** findings suggest that electro acupuncture at Baihui acupoint could effectively increase m RNA expression of molecules involved in Neuro D in the brains of newborn rats exposed to in utero fetal distress.