Regioselective and Stereoselective Synthesis of the 3-Aryl-4- phosphoryl-1, 2, 4-triazoline-5-ones

作     者：De Xin FENG Ru Yu CHEN You HUANG 

作者机构：Institute of Elemento-Organic Chemistry National Key Laboratory of Elemento-Organic Chemistry Nankal University Tianjin 300071 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2006年第17卷第9期

页      面：1145-1148页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the NNSFC(No.20172027) the Natural Science Foundation of Tianjin(05YFJMJC00600)for financial support 

主　　题：Triazoline 1-acylthiosemicarbazides regioselective stereoselective cyclization. 

摘      要：A novel and efficient route of synthesizing 1, 2, 4-triazoline-5-ones is reported. The title compounds can be prepared in high yield and purity by the one-pot oxidation and cyclization of 1-acylthiosemicarbazides. The reaction is regioselective and stereoselective. The reaction condition is mild.