Recent progresses in stem cell research and hearing restoration

作     者：YANG Hua, CHEN Xiao-wei, GAO Zhi-qiang Department of Otolaryngology, Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing, China, 100730 

作者机构：Department of Otolaryngology Chinese Academy of Medical Sciences Peking Union Medical College Hospital Beijing 100730 China 

出 版 物：《Journal of Otology》 (中华耳科学杂志（英文版）)

年 卷 期：2008年第3卷第1期

页      面：1-8页

学科分类：1003[医学-口腔医学] 1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学] 

基　　金：the Beijing Scienceand Technology NOVA program Grant (No.2006B53) the Peking Union Medical CollegeHospital Junior Researcher Grant 

主　　题：stem cell Recent progresses in stem cell research and hearing restoration 

摘      要：Serious hearing and balance impairments can occur as a result of loss of hair cells related to aging, environmental stresses(such as noises exposure) or exposure to chemotherapeutic drugs(such as cisplatin and aminoglycoside antibiotics). Because a large portion of hearing impairment involves loss of hair cells, regeneration or replacement of these cells is a possible alternative to prosthetic devices1. Researchers have paid hot attention to the study of inner ear hair cell regeneration for hearing restoration for many years. Besides the important function of hair cells, there are many other contributors essential for normal hearing. Hair cell regeneration is one of the essential steps for total hearing recovery, but not the only one. In this article, we will review the progresses in research on hearing loss, stem cell application and hearing restoration.