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Estrogen sulfotransferase regulates inflammatory response and lipid metabolism of human endothelial cells via PPARγ

Estrogen sulfotransferase regulates inflammatory response and lipid metabolism of human endothelial cells via PPARγ

作     者:XU Ya-li,TIAN Dai,WANG Zheng-yang,LI Meng-meng,NING Yan-xia,CHEN Si-feng,LI Xiao-bo,YIN Lian-hua (Department of Physiology and Pathophysiology,Fudan University Shanghai Medical College,Shanghai 200032,China) 

出 版 物:《中国病理生理杂志》 (Chinese Journal of Pathophysiology)

年 卷 期:2012年第11期

页      面:2036-2037页

核心收录:

学科分类:1001[医学-基础医学(可授医学、理学学位)] 100104[医学-病理学与病理生理学] 10[医学] 

基  金:General Program(No.81170253) Young Scientists Fund(No.30800547)of National Natural Science Foundation of China 

主  题:Estrogen sulfotransferase regulates inflammatory response and lipid metabolism of human endothelial cells via PPAR HUVECs 

摘      要:Estrogen sulfotransferase(SULT1E1)is a phase II drug-metabolizing enzyme known to catalyze sulfoconjugation of estrogens.17β-estradiol(E)plays a pivotal role in attenuating endothelial *** be further sulfated to estradiol sulfate(ES)u-

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