Framework Nucleic Acids for Cell Imaging and Therapy
作者机构:School of Chemistry and Chemical Engineeringand Institute of Molecular MedicineRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200240P.R.China
出 版 物:《Chemical Research in Chinese Universities》 (高等学校化学研究(英文版))
年 卷 期:2020年第36卷第1期
页 面:1-9页
核心收录:
学科分类:071011[理学-生物物理学] 0710[理学-生物学] 07[理学]
基 金:Supported by the Shanghai Pujiang Program China
主 题:DNA nanotechnology Framework nucleic acid DNA origami Therapy Cellular imaging
摘 要:Over the past decade,structural DNA nanotechnology has been well developed to be a promising and powerful technique to generate various nanostructures with programmability,spatial organization and *** the advent of computer-aided tools,framework nucleic acids have been employed in a series of biomedical applications,ranging from biosensing,bioimaging,diagnosis,to *** this review,we summarized recent advances in the construction of precisely assembled DNA nanostructures,and DNA-engineered *** also outlined the challenges and opportunities for the translational applications of framework nucleic acids.