Catastrophic gastrointestinal complication of systemic immunosuppression
Catastrophic gastrointestinal complication of systemic immunosuppression作者机构：Gastroenterology Unit Glasgow Royal Infirmary Department of Pathology Southern General Hospital Glasgow
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2015年第21卷第8期
页 面：2542-2545页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Immunosuppression Cytomegalovirus Gastrointestinal
摘 要：We present a case of acute upper gastrointestinal haemorrhage in a patient with systemic vasculitis immunosuppressed on cyclophosphamide and *** patient presented with a diffuse haemorrhagic oesophagitis and a non-specific *** taken from the oesophagus and duodenum demonstrated infection with herpes simplex virus(HSV)and cytomegalovirus(CMV)*** infection of the upper gastrointestinal tract is a recognised complication of immunosuppression and HSV is one of the most common *** on the other hand most commonly causes a colitis or less commonly *** enteritis is rare as is the synchronous infection with two viral agents in an immunocompromised patient having being described in a few case series *** infection of the gastrointestinal tract in immunocompromised patients should be treated with systemic anti-viral medication and consideration to withdrawal of the immunosuppressive therapy if possible and *** authors highlight the need for a high suspicion of viral infection in immunosuppressed patients presenting with upper gastrointestinal bleeding.
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