体位性低血压和晕厥与ChiariⅠ型畸形有关

作     者：Prilipko O. Dehdashti A.R. Zaim S. Seeck M. 方伯言 

作者机构：Presurgical Epilepsy Evaluation Unit Department of Neurology H.eve 24 opital Cantonal Universitaire de Gen' rue Micheli-du-Crest CH-1211 Gen'eve 14 Switzerland Dr. 

出 版 物：《世界核心医学期刊文摘（神经病学分册）》 (Digest of the World Core Medical Journals:Clinical Neurology)

年 卷 期：2005年第1卷第10期

页      面：36-36页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Chiari 体位性低血压 小脑扁桃体疝 心动过速 枕骨大孔 枕部疼痛 基底动脉 POTS 调节中枢 临床症状 

摘      要：The Chiari type I malformation (CM1) is characterized by herniation of cerebe llar tonsils to at least 3- 5 mm below the plane of foramen magnum and can pres ent with a wide variety of clinical symptoms, frequently including occipital hea daches, secondary to bulbar and/or medullary distress. Rarely, syncopal episodes have also been described and attributed to either compression of the midbrain a scending reticular system, or vascular compromise (vertebrobasilar artery compre ssion, hypotension). We report the first case of a CM1 patient with frequently r ecurring syncope due to postural orthostatic tachycardia syndrome (POTS), a form of orthostatic intolerance, whose symptoms resolved completely after surgical i ntervention. It is important to stress that it is not clear whether the describe d association of POTS and CM1 in our patient is a fortuitous finding in an isola ted case or a reflection of a more systematic association between the two pathol ogies.