Micro-computed tomography for small animal imaging: Technological details

作     者：Hao Li, Hui Zhang , Zhiwei Tang, Guangshu Hu Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China 

作者机构：Department of Biomedical Engineering Tsinghua University Beijing 100084 China 

出 版 物：《Progress in Natural Science:Materials International》 (自然科学进展·国际材料(英文))

年 卷 期：2008年第18卷第5期

页      面：513-521页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071002[理学-动物学] 

基　　金：National Key Basic Research Program For Youth  (2006CB705700) 

主　　题：Micro-computed tomography Small animal X-ray 

摘      要：The high-resolution micro-computed tomography (micro-CT) system has now become an important tool for biological research. The micro-CT system enables a non-invasive inspection to screen anatomical changes in small animals. The promising advantages include high-spatial resolution, high sensitivity to bone and lung, short scan time and cost-e ectiveness. The dose received by the small animal might be a critical concern in the research. In this article, the choice of the components, fundamental physical problems, the image recon- struction algorithm and the representative applications of micro-CT are summarized. Some results from our research group are also pre- sented to show high-resolution images obtained by the micro-CT system.