Effectiveness of Echinochrome on HFD‑Induced Hyperlipidemia in Rats

作     者：Sohair R.Fahmy Nashwah Ismail Zaki Shaimaa Zakaria Eid Ayman Saber Mohamed Sarah S.Hassanein 

作者机构：Zoology DepartmentFaculty of ScienceCairo UniversityGiza 12613Egypt Physiology DepartmentNational Organization for Drug Control and ResearchCairoEgypt 

出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)

年 卷 期：2019年第9卷第5期

页      面：337-344页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：High-fat diet Atorvastatin Echinochrome Obesity Oxidative stress 

摘      要：Obesity has been identified with an expanded danger of a progression of illnesses that include different organ-frameworks of the *** the present examination,we evaluated the hypolipidemic properties of Echinochrome(Ech)pigment in a high-fat diet(HFD)induced hyperlipidemia in *** the hyperlipidemic model was set up,rats were haphazardly separated into five groups as follows:normal control group,HFD group,Atorvastatin(ATOR)group(80 mg/kg),Ech group(1 mg/kg)and combined group ATOR+*** outcomes demonstrated that Ech improves lipid profile,liver functions,kidney functions and antioxidant markers of obese *** findings of the present investigation indicated that the Ech possesses hypolipidemic potential in obese rats.