Carcinoma ex pleomorphic adenoma of the trachea: A case report

作     者：Heng-Xing Gao Quan Li Wen-Li Chang Ya-Long Zhang Xiao-Zhi Wang Xue-Xue Zou 

作者机构：Respiratory DepartmentBinzhou Medical University HospitalBinzhou 256603Shandong ProvinceChina Department of RadiologyBinzhou Medical University HospitalBinzhou 256603Shandong ProvinceChina Department of PathologyBinzhou Medical University HospitalBinzhou 256603Shandong ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2019年第7卷第17期

页      面：2623-2629页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

主　　题：Case report Carcinoma ex pleomorphic adenoma Trachea Pleomorphic adenoma 

摘      要：BACKGROUND Carcinoma ex pleomorphic adenoma (CXPA) is defined as a malignant salivary gland tumor arising from a primary or recurrent pleomorphic adenoma.Only three cases of CXPA of the trachea have been reported in the literature.CASE SUMMARY We report a case of tracheal CXPA in a 55-year-old woman,who presented with a more than 3-mo history of progressive dyspnea.Computed tomography of the neck and thorax revealed an inhomogeneous,broad-based lesion arising from the tracheal wall on the right side.Endoscopy revealed a subglottic neoplasm causing up to 90% luminal stenosis.The tumor was resected using a highfrequency electrosurgical snare combined with argon plasma coagulation.Histopathology and immunohistochemistry revealed that the tumor was a CXPA of the trachea.CONCLUSION We report the fourth case of tracheal CXPA,and present the first instance of resection of CXPA using high-frequency electrosurgical snare and laser ablation.We also discuss the pathogenesis,diagnosis,histopathology,and systemic therapy of this rare disease.