A new variant of Knorr's pyrrole synthesis

作     者：ZHANG,Yan JIANG,Yun-Zhen LIANG,Xiao-TianInstitute of Materia Medico,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100050,China 

作者机构：Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100050 China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：1997年第15卷第4期

页      面：371-378页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：Pyrrole synthesis ethyl 3-bromopyruvate anilines ketones 

摘      要：The reaction between ethyl 3-bromopyruvate and p-substituted anilines was found to involve the unexpected participation of acetone (solvent) forming *** influence of p-substituents of aniline and the feasibility with other ketones were studied.N-aryl-indole-3-carboxylate (17) was synthesized successfully with this *** unique character of p-methoxy-aniline in this reaction was discussed.