Prophylactic effect of glyceryl trinitrate on post-endoscopic retrograde cholangiopancreatography pancreatitis:A randomized placebo-controlled trial

作     者：Jian-Yu Hao Dong-Fang Wu Yue-Zeng Wang Ying-Xin Gao Hai-Po Lang Wei-Zhen Zhou 

作者机构：Department of Digestion Beijing Chaoyang Hospital Affiliated to Capital Medical University Beijing 100020 China 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2009年第15卷第3期

页      面：366-368页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Glyceryl trinitrate Cholangiopancreatography Endoscopic retrograde Pancreatitis 

摘      要：AIM:To examine the prophylactic effect of glyceryl trinitrate on post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis and ***:Patients scheduled for ERCP were randomly divided into study group and placebo *** in study group and placebo group were treated with 5 mg glyceryl trinitrate and 100 mg vitamin C,respectively,5 min before endoscopic ***:A total of 74 patients were enrolled in the final ***-ERCP pancreatitis occurred in 3 patients(7.9%) of the study group and 9 patients(25%) in the placebo group(P = 0.012).Hyperamylasemia occurred in 8 patients of the study group(21.1%) and 13 patients(36.1%) of the placebo group(P = 0.037).CONCLUSION:Glyceryl trinitrate before ERCP can effectively prevent post-ERCP and hyperamylasemia.