Effectiveness of vedolizumab treatment in two different anti-tumor necrosis factor alpha refractory pouchitis: A case report
作者机构：Department of Gastroenterology and Hepatology Alanya Alaaddin Keykubat University School of Medicine
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2019年第7卷第16期
页 面：2316-2321页
核心收录：
主 题：Anti-tumor necrosis factor alpha Refractory pouchitis Vedolizumab Ulcerative colitis
摘 要：BACKGROUND Refractory pouchitis is a common cause of pouch failure,which may require surgical excision of the pouch or permanent *** aimed to show the effect of vedolizumab on treatment of the patient with refractory *** SUMMARY A 32-year-old male with pancolonic ulcerative colitis since the age of 25 with primary failure of infliximab and mesalamine and intolerance of azathioprine,underwent a total proctocolectomy with ileal pouch-anal anastomosis in *** developed chronic diarrhea in 2014,which was watery,30 per day and accompanied with blood and mucus affecting his quality of *** Vedolizumab is safe and effective in the management of anti-tumor necrosis factor alpha refractory pouchitis.
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