Multifocal G1-G2 gastric neuroendocrine tumors:Differentiating between Type Ⅰ, Ⅱ and Ⅲ, a clinicopathologic review

作     者：Khaled Algashaamy Monica Garcia-Buitrago 

作者机构：Department of Pathology and Laboratory Medicine Jackson Memorial Hospital University of Miami Miller School of Medicine 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2019年第7卷第17期

页      面：2413-2419页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Gastric neuroendocrine tumors Enterochromaffin like cells Histopathological features Immunohistochemistry Diagnosis Treatment 

摘      要：Gastric neuroendocrine tumors (gNETs) are a rare entity that is increasing in *** pathophysiological processes can lead to the development of these tumors,appropriate histological analysis is necessary to differentiate between grade 1 (G1) and grade 2 (G2) tumors as this will impact the management of these patients based on their increased risk of lymph node and distant *** provide a comprehensive clinicopathologic review of multifocal gastric neuroendocrine tumors,with particular emphasis on G1 and G2 tumors and differentiating between types I,II and II and risk stratification based upon immunohistochemical *** review is based on peer-reviewed literature and the authors’ *** are a heterogenous group of tumors that is rising in *** lesions while arise from the same cell type,they have different *** the type of gNETs is a collective effort of clinical and pathologic *** correct grading and staging of these lesions are of paramount significance,due its impact on patient management and prognosis.