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Atrial fibrillation ablation in patients with heart failure review

Atrial fibrillation ablation in patients with heart failure review

作     者:Mohammad I. Amin Laurence D. Sterns Richard A. Leather Anthony S. Tang 

作者机构:Department of Cardiology Royal Jubilee Hospital Victoria Canada 

出 版 物:《World Journal of Cardiovascular Diseases》 (心血管病(英文))

年 卷 期:2013年第3卷第1期

页      面:49-57页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Atrial Fibrillation Ablation Heart Failure 

摘      要:Atrial fibrillation and heart failure often coexist in patients with advanced heart failure symptoms. The result, in addition to a significant impact on quality of life, is an increase in the risk of a adverse clinical outcomes including stroke, hospitalization and overall mortality. Pharmacological therapy for atrial fibrillation in the heart failure population remains limited due to sub-optimal drug efficacy and a likely increased mortality due to pro-arrhythmia. Atrial fibrillation ablation, since it allows for therapy without the need for toxic medication, has the potential to become mainstream treatment in patients with drug refractory, symptomatic atrial fibrillation and heart failure. Randomized studies and observational data suggest that atrial fibrillation ablation provides superior rhythm control to anti-arrhythmic drugs. Atrial fibrilla- tion ablation is relatively safe and may result in improvement of left ventricular function and quality of life. Ongoing studies are attempting to assess a number of outcome measures to help define its role in the heart failure patient population. This review focuses on atrial fibrillation ablation in patients with congestive heart failure, and summarizes the results of available literature.

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