烟碱和大脑功能障碍(英文)
Nicotine and brain disorders作者机构：Departamento de Fisiología Facultad de Medicina Departamento de Fisiología Facultad de Medicina Depto de Neurociencias Instituto de Fisiología Celular Universidad Nacional Autónoma de México Míxico
出 版 物：《Acta Pharmacologica Sinica》 (中国药理学报(英文版))
年 卷 期：2000年第21卷第2期
页 面：3-10页
核心收录：
学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学]
主 题：烟碱 烟碱受体 帕金森病 阿尔采末病 多动秽语综合征 轻微脑损伤综合征 抑郁症 精神分裂症
摘 要：During the last decade, brain nicotinic acetylcholine receptors were extensively characterized from electrophys-iological and pharmacological points of view. These receptors play important roles in memory and cognition and participate in the pathogenesis of several brain disorders (Parkinson s and Alzheimer s diseases, Tourette s syndrome, schizophrenia, depression, attention deficit disorder) . In the same diseases, clinical studies showed that nicotine had beneficial effects, both as therapeutic and prophylactic agent. This review presents recent data concerning the structure and properties of neuronal nicotinic receptors, their involvement in the pathogenesis of various brain disorders and the beneficial effects of nicotine as therapeutic agent.
同方期刊数据库