HLA antigens and anti-sperm antibody production in Iranian vasectomized men

作     者：Gholamreza Azizi Saeed Namaki Abbas Mirshafiey Kabir Magaji Hamid 

作者机构：Imam Hassan Mojtaba HospitalAlborz University of Medical Sciences Department of Pathobiology Faculty of Paramedical Sciences Shahid Beheshti University of Medical Sciences Department of Immunology School of Public Health Tehran University of Medical Sciences 

出 版 物：《The Journal of Biomedical Research》 (生物医学研究杂志（英文版）)

年 卷 期：2015年第29卷第1期

页      面：87-90页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：HLA antigens and anti-sperm antibody production in Iranian vasectomized men ASA 

摘      要：Dear Editor： Anti-sperm antibodies （ASAs） are composed of numerous antibodies interacting with multiple sperm antigens that play a role in fertility. In males, ASAs cause ＇immune infertility＇ by decreasing sperm counts and normal forms, as well as reducing sperm motility and viability, markedly reducing the likelihood of natural conception. The development of ASA in the male depends on the release of sequestered antigens on germ cells following the disruption of the blood-testis barrier.