Long-term prognosis and prognostic determinants of patients with first attack of mild and moderate ischemia at Beijing community hospitals

作     者：Xianghua Fang Liming Li Xinqing Zhang Hongjun Liu Hongmei Zhang Xiaoming Qin 

作者机构：Department of Epidemiology ＆ Biostatistics School of Public Health Peking University Health Sciences Center Beijing 100191 China Department of Evidence-based Medicine Xuanwu Hospital Capital Medical University Beijing 100053 China Department of Neurology Xuanwu Hospital Capital Medical University Beijing 100053 China Department of Geriatrics Xuanwu Hospital Capital Medical University Beijing 100053 China 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2012年第7卷第7期

页      面：540-545页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 07[理学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 0822[工学-轻工技术与工程] 082203[工学-发酵工程] 071003[理学-生理学] 

基　　金：supported by the National Natural Science Foundation of China  No. 30671797 and 81072361 

主　　题：ischemic stroke follow-up study predictors prognosis recurrent stroke survival 

摘      要：A total of 710 patients with first-ever ischemic stroke were consecutively recruited between January 2003 and December 2004 from five community hospitals/stations in five districts of Beijing, China. As of December 31, 2008, a total of 2 477 person-years were followed-up. During the five-year follow-ups, 117 adverse events occurred, including all-cause death and acute cardiovascular events （recurrent stroke, acute myocardial infarction, and sudden death）. The five-year cumulative mortality rate was 2.18/100 person-years （54 cases）, with 3.88/100 person-years （96 cases） of acute cardiovascular events and 3.02/100 person-years （75 cases） of recurrent stroke. Multiple factor analyses using the Cox proportional hazards ratio models showed that age, diabetes, and dependence of activities of daily living were independent predictors for death, acute cardiovascular disease events, or recurrent stroke. The results demonstrated that recurrent stroke was a major vascular disease that affected the prognosis of mild or moderate stroke patients. Secondary prevention of stroke patients should include active management of vascular risk factors and rehabilitation.