Synthesis of urea acetates as potential PPARα/γ dual agonists
Synthesis of urea acetates as potential PPARα/γ dual agonists作者机构：Key Laboratory of Asymmetric Synthesis ＆ Chirotechnology of Sichuan Province and Union Laboratory of Asymmetric Synthesis Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 China Graduate School of Chinese Academy of Sciences Beijing 100049 China
出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)
年 卷 期：2008年第19卷第2期
页 面：166-168页
核心收录：
学科分类：1007[医学-药学(可授医学、理学学位)] 10[医学]
基 金：Chengdu Institute of Organic Chemistry Chinese Academy of Sciences, CAS
主 题：Oxazolc PPAR agonist Type 2 diabetes Urea Ammonolysis Synthesis
摘 要：In the quest for novel PPARα/γ dual agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we designed and synthesized a series of urea acetates as potential PPARα/γ dual agonists. The structure of the target compounds, intermediates were characterized by ^1H N-MR, HRMS.
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