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Synthesis, Structure and Antibacterial Activities of 4-BBTS Schiff Base and Its Complexes

Synthesis, Structure and Antibacterial Activities of 4-BBTS Schiff Base and Its Complexes

作     者:LI Pei-Fan LIU Bin WANG Jin-Ling 

作者机构:Pharmacy Department of Tianjin Medical College Tianjin 300222 China College of Chemistry and Life Tianjin Normal University Tianjin 300074 China 

出 版 物:《Chinese Journal of Structural Chemistry》 (结构化学(英文))

年 卷 期:2007年第26卷第2期

页      面:224-228页

核心收录:

学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基  金:This work was supported by the Natural Science Foundation of Tianjin (No. 003601711) 

主  题:4-BBTS Schiff base synthesis structure antibacterial activity 

摘      要:4-Bromobenzaldehyde thiosemicarbazone Schiff base (4-BBTS) and its Cu(Ⅱ), Zn(Ⅱ), Co(Ⅱ) and Ni(Ⅱ) complexes were synthesized and characterized by elemental analysis, UV, IR, MS, ^1H NMR, and molar conductivity. Using disc diffusion method, the antibacterial activity tests were conducted. The results revealed that the ligand as well as all the complexes exhibits good antibacterial activities against E. Coli. and S. Aureus. Moreover, Cu(Ⅱ) complex shows the best antibacterial activity, which provides beneficial reference for studying the relationship between the structures and performances.

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