Pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia:report of a case

作     者：Rajkumar Krishnasamy Shaleen Agarwal Shivendra Singh Sunil Puri Puja Sakhuja Anil K Agarwal 

作者机构：Department of Gastrointestinal SurgeryGovind Ballabh Pant Hospital and Maulana Azad Medical College(Delhi University)New Delhi 110002India Department of RadiologyGovind Ballabh Pant Hospital and Maulana Azad Medical College(Delhi University)New Delhi 110002 Department of PathologyGovind Ballabh Pant Hospital and Maulana Azad Medical College(Delhi University)New Delhi 110002 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2007年第6卷第5期

页      面：553-556页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：pancreatectomy pancreatic ductal carcinoma chronic pancreatitis 

摘      要：BACKGROUND:The presence of pancreatic ductal intraepithelial neoplasia in patients with chronic pancreatitis is a risk factor for development of pancreatic adenocarcinoma. METHOD:A case of pancreatic ductal adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia was diagnosed in the setting of chronic pancreatitis. RESULTS:Distal pancreatectomy combined with splenec- tomy was performed with a diagnosis of pancreatic body carcinoma.Histopathological examination suggested adenocarcinoma associated with pancreatic ductal intraepithelial neoplasia.The tumor was detected in the remaining head of the pancreas,for which a total pancreatectomy was done. CONCLUSIONS:When a patient with pancreatic ductal intraepithelial neoplasia associated with adenocarcinoma of the pancreas in the setting of chronic pancreatitis is at an increased risk of recurrence in the remaining pancreatic parenchyma,total pancreatectomy may be feasible.